SAMiRNA® - AR68 Micellar Delivery System

At 100nm, SAMiRNA® penetrates hair follicle openings—averaging 600,000nm—via massage, reaching areas where AR is present within the follicle.

Science-driven innovation featured in follicular delivery

A patented micellar RNA platform that uses self-assembling nanoparticle micelles to pass through the scalp barrier via massage—without needles, hormones, or chemical modification.

 
Patented Micellar RNA

Self-assembling nanoparticle micelles for follicle delivery

Stable at Room Temperature

No cold-chain required, easy clinic storage

Bypasses Innate Immune Stimulation

Natural RNA composition, mild and safe for long-term use

Topical + Massage Application

Silicone tip enhances absorption through follicle openings

High Delivery Efficiency

Biocompatible polymer conjugation for AR-related follicular delivery

Scalp Absorption Timeline

After application to scalp—ingredient gradually absorbs into hair follicles

Scientific Reports – NATURE PORTFOLIO

Mode of Action & Cosmetic Application Study of SAMiRNA™:
Supporting scalp health and improving the appearance of thinning hair associated with lifestyle and age-related changes

EMJ DERMATOLOGY

Featured as an innovative RNA-based scalp care cosmetic with follicle-targeting delivery

91%

Participants reported scalp improvement
CRO Ellead clinical evaluation

7.5

New hair strands per cm² (terminal hair)
Scientific Reports, 2023

× 600K

Nanoparticle vs. avg. scalp pore — deep follicular access
Patent No.

Structured Clinical Program

Flexible, phased treatment for clinical continuity

Enrollment note:

Typical 6-month program requires 2~3 kits per patient.
Homecare extension (CosmeRNA Daily Routine) recommended from month 6 onward

 

INITIATION

Weekly Sessions
Weeks 1-4 to 8

Establish follicular uptake with weekly in-clinic applications. Builds baseline concentration for sustained effect. Higher-frequency for patients with significant thinning.

PROGRESSION

Biweekly Transition
Weeks 8–24+ (≥16weeks)

Sustained improvement phase. Consider introducing CosmeRNA Daily Routine homecare during this phase to extend and reinforce clinical results between visits.

MAINTENANCE

Monthly + Homecare
Month 6 onward

Monthly in-clinic touchpoints with integrated homecare continuity for long-term scalp health maintenance and patient retention in the program.

From Clinic to Confidence

Watch the full application walkthrough—designed to help you and your team deliver a consistent, professional experience that patients will see and feel.

 
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